Variants in ETV6, which encodes a transcription repressor of the E26 transformation-specific family, have recently been reported to be responsible for inherited thrombocytopenia and hematologic malignancy.We sequenced the DNA from cases with unexplained dominant thrombocytopenia and identified six likely pathogenic variants in ETV6, of which five a
Ruo-Wen Chen,1,2 Hui Liu,2 Jian-Xiong An,1,2 Xiao-Yan Qian,2 Yi-De Jiang,2 Doris K Cope,3 John P Williams,3 Rui Zhang,1 Li-Na Sun1 1Department of Anesthesiology, Weifang Medical University, Weifang City, Shandong, 2Department of Anesthesiology, Pain Medicine and Critical Care Medicine, Aviation General Hospital of China Medical University and Beiji
RNA methylation is a novel epigenetic modification that can be used to evaluate tumor prognosis.However, the underlying mechanisms are unclear.This study aimed to investigate the genetic characteristics of 5-methylcytosine (m5C) and N1-methyladenosine (m1A) regulators in lung squamous cell carcinoma (LUSC) and the prognostic value and immune-relate
Next-generation sequencing (NGS) panels are used widely in clinical diagnostics to identify genetic causes of various monogenic disease groups including neurometabolic disorders and, more recently, lysosomal storage disorders (LSDs).Many new challenges have been introduced through these new 1980 corvette tail lights technologies, both at the labora
Spectrum sensing vulnerabilities in cognitive radio networks can significantly degrade performance.Most disruption attacks in the current literature involve spoofing of the free bands used for sensing by making them appear busy.In this study, we proposed a different approach for sensing disruptions.We examined the optimal strategy for an intelligen